Colossians 4:3

Withal praying also for us, that God would open unto us a door of utterance, to speak the mystery of Christ, for which I am also in bonds:

Paul's request is a call for believers to pray for gospel workers that God would open to them a door of utterance to speak the mystery of Christ. That door means both opportunity and words to make the mystery known. Such prayer upholds the work of winning souls even when those proclaiming the message are in bonds for it, and it belongs with watching in prayer and with speech seasoned with grace so as to represent Christ. The verse requires more than reading the Word of life; believers are to study it prayerfully so they can present the truth to unbelievers in the right manner. The light received from the Word is to be imparted to others so that they become interested in studying the Scriptures themselves.

The open door is opportunity and favor that God gives to workers who labor earnestly, prayerfully and humbly in the spirit of Christ. It comes to those who set a right and self-sacrificing example without seeking more for themselves, so that people see their self-denial and the blessing of the Lord rests upon them. Those doors often open when medical missionary work relieves suffering and overcomes prejudice, allowing the Word to find entrance, including among people in heathen countries. This promise applies to women trained in medical missionary lines who go to heathen countries to help sisters in need, whose work for others prepares the way for the word to enter.

The openings are providential opportunities to reach hearts and impart truth. Christians should be ready to use their speech to help people who do not know God. Workers are to plead for God to open the way for truth to be proclaimed where people have not been warned and are perishing in sin. Because that work is urgent it should not be delayed.