Dĭs'in-ūre', v. t.

v. t. [imp. & p. p. DISINURED; p. pr. & vb. n. DISINURING.] [Prefix dis and inure, q. v.] To deprive of familiarity or custom; to render unfamiliar. [Obs.]

We are hindered and disinured . . . toward the true knowledge. Milton.