In-sāne',, a.
a. [Prefix in, not, and sane; Lat. insanus, It. & Sp. insano.]
Sense 1. Exhibiting unsoundness of mind; mad; deranged in mind; delirious; distracted.
Soon after Dryden's death she became insane, and was confined under the care of a female attendant. Malone.
I know not which was the insane measure. Southey.
Sense 2. Used by, or appropriated to, insane persons; as, an insane hospital.
Sense 3. Making mad; causing madness. [Obs.]
Or have we eaten of the insane root That takes the reason prisoner? Shak.