Ma-lig'nan-cy

Sense 1. The quality of being malignant; extreme malevolence; bitter enmity; malice; as, malignancy of heart.

Sense 2. Unfavorableness; unpropitiousness.

The malignancy of my fate might distemper yours. Shak.

Sense 3. (Med.) Virulence; tendency to mortification or to a fatal issue; as, the malignancy of an ulcer or of a fever.

Synonyms—Malice; malevolence; malignity. See MALICE.