Vĭ-cĭs'ĭ-tūde, n.
(53), n. [Fr. vicissitude, Sp. vicisitud, Pg. vicissitude, It. vicissitudine, Lat. vicissitudo, from vicis, change, turn.] 1. Regular change or succession from one thing to another; alternation; mutual succession; interchange.
God made two great lights . . . To illuminate the earth and rule the day In their vicissitude, and rule the night. Milton.
Sense 2. Change; revolution; mutation, as in human affairs.
This man had, after many vicissitudes of fortune, sunk at last into abject poverty. Macaulay.